Hot melt extrusion (HME) has emerged as a pivotal technology in the pharmaceutical industry, offering a solvent-free, continuous process for producing various drug delivery systems. This technology has gained significant attention due to its ability to enhance the solubility and bioavailability of poorly soluble drugs, develop abuse-deterrent formulations, and create customized drug delivery systems. In this article, we will explore the latest innovations in hot melt extrusion technology, including advancements in equipment, applications, and process analytical technologies.

Aluminum extrusion is a widely used manufacturing process for shaping aluminum into desired profiles. However, issues can arise during the extrusion process, leading to problems such as under-extrusion or complete failure to extrude. Understanding the common causes of these issues and how to troubleshoot them is essential for anyone working with aluminum extruders. This article will explore various reasons why your aluminum extruder may not be extruding properly, along with solutions and preventive measures.